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Such targeting mechanisms, combined with pH-responsive drug release in tumor microenvironments (demonstrated by 80% cumulative 5-FU release from DF-TAPB-COF at pH 5.0), create spatially controlled delivery systems

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The immature frontal lobe makes teens prone to: Risk-taking Impulsivity Difficulty foreseeing long-term consequences Susceptibility to peer or social media influence For teens with ADHD and mood disorders, these vulnerabilities are even stronger

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